Asymmetric synthesis of cyclopentanes bearing four contiguous stereocenters via an NHC-catalyzed Michael/Michael/esterification domino reaction.

6533b7d4fe1ef96bd12631f8

RESEARCH PRODUCT

Asymmetric synthesis of cyclopentanes bearing four contiguous stereocenters via an NHC-catalyzed Michael/Michael/esterification domino reaction.

Kun Zhao Xiaoxiao Song Tianyu Wu Qijian Ni Rakesh Puttreddy Tao Shu Kari Rissanen Dieter Enders

subject

Cyclopentanes Stereochemistry 010402 general chemistry 01 natural sciences Catalysis Domino Catalysis Stereocenter Cascade reaction domino reaction Materials Chemistry ta116 cyclopentane motifs 010405 organic chemistry Chemistry Metals and Alloys Enantioselective synthesis General Chemistry 540 0104 chemical sciences 3. Good health Surfaces Coatings and Films Electronic Optical and Magnetic Materials Chemistry ddc:540 Ceramics and Composites

description

An NHC-catalyzed Michael/Michael/esterification domino reaction via homoenolate/enolate intermediates for the asymmetric synthesis of tetrasubstituted cyclopentanes is described.

year	journal	country	edition	language
2016-01-12	Chemical communications (Cambridge, England)

10.1039/c5cc09581f https://pubmed.ncbi.nlm.nih.gov/26750327

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