6533b7d6fe1ef96bd126648e

RESEARCH PRODUCT

Muscarinic Receptor Activation Increases Efflux of Choline from Isolated Heart and Rat Cortex in Vivo. Interactions with Forskolin and IBMX

Konrad LöffelholzR. LindmarR. Brehm

subject

medicine.medical_specialtyIBMXGlycogenolysisForskolinCentral nervous systemMuscarinic acetylcholine receptor M2NeurotransmissionPharmacologychemistry.chemical_compoundEndocrinologymedicine.anatomical_structurechemistryInternal medicineMuscarinic acetylcholine receptormedicineCholine

description

Muscarinic receptor activation modulates functions of the heart and neurotransmission in the peripheral and central nervous system. Moreover, muscarinic agonists produce changes in the metabolism of, for example, heart tissue, such as inhibition of beta-adrenoceptor-mediated cAMP accumulation, glycogenolysis and lipase activation.

https://doi.org/10.1007/978-1-4684-5194-8_62