6533b7d7fe1ef96bd1268db9
RESEARCH PRODUCT
SUL METABOLISMO DEGLI ORGANI DI RATTO PORTATORE DI SARCOMA DA BENZOPIRENE
T TerranovaV. Castrosubject
chemistry.chemical_classificationCancer ResearchBearing (mechanical)General MedicineMetabolismmedicine.disease030218 nuclear medicine & medical imaginglaw.inventionAmino acid03 medical and health sciences0302 clinical medicineOncologychemistrylaw030220 oncology & carcinogenesismedicineCancer researchSarcomadescription
Free aminoacids were estimated in benzopyrene sarcoma of rats and in some organs of the tumour-bearing rats (brain, heart, muscle, lung, liver, spleen, kidney). In the tumour the content changes according to the growth stage; in the advanced tumour a strong increase of serine-glycine, glutammic acid and treonine is observed. In the organs the free amino acid contents are diminished in the first stages of the tumour growth, while in the advanced stages there is a tendency to an increase with different values according to the organs. The oxidation process in the organ homogenate (with or without substrate addition) varies according to the stage of the tumour growth, more evidently in the organs showing a large modification of the amino acids contents.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1955-05-01 | Tumori Journal |