6533b7d8fe1ef96bd1269bbd

RESEARCH PRODUCT

Hepatic focal nodular hyperplasia: contrast-enhanced ultrasound findings with emphasis on lesion size, depth and liver echogenicity

Roberto LagallaG MaliziaAdele TaibbiDomenica MatrangaTommaso Vincenzo BartolottaMassimo Midiri

subject

AdultMalemedicine.medical_specialtyAdolescentStatistics as TopicSulfur HexafluorideContrast MediaSensitivity and SpecificityMicrobubbleLesionYoung AdultFocal nodular hyperplasia Ultrasonography Contrast media Microbubbles Liver diseasesmedicineHumansRadiology Nuclear Medicine and imagingLiver diseasesPhospholipidsAgedUltrasonographyNeuroradiologyObserver Variationmedicine.diagnostic_testbusiness.industryUltrasoundFocal nodular hyperplasiaReproducibility of ResultsEchogenicityInterventional radiologyGeneral MedicineMiddle Agedmedicine.diseaseFocal Nodular HyperplasiaMicrobubblesFemaleRadiologymedicine.symptomSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessContrast-enhanced ultrasound

description

To correlate contrast-enhanced ultrasound (CEUS) findings of hepatic focal nodular hyperplasia (FNH) with lesion size, depth and liver echogenicity and to compare CEUS with baseline US. Two radiologists evaluated baseline US and CEUS examinations of 92 FNHs (mean size: 3.1 +/- 1.7 cm) in 71 patients (59 women and 12 men) to detect the "spoke-wheel" sign, central scar and feeding vessel. The FNHs were grouped and analysed by dimension, depth and liver echogenicity. At least one sign could be detected at CEUS in 27 out of 36 (75%) FNHs larger than 3 cm and in 17 out of 56 (30%) FNH measuring 3 cm or less (p 0.05) as well as between CEUS or baseline US/CD with regard to lesion size, depth or liver echogenicity (p > 0.05). The detection rate of the central scar and spoke-wheel sign in FNH at CEUS is strongly dependent on lesion size and CEUS can confidently diagnose most FNHs larger than 3 cm.

yearjournalcountryeditionlanguage
2010-04-21European Radiology
https://doi.org/10.1007/s00330-010-1775-x