6533b7d8fe1ef96bd126a18b

RESEARCH PRODUCT

Zum Einfluss von Angiotensin II auf die Nebennierenrinde unter chemischer adrenostase mit SU 4885 (Metopiron)

D. VothH. Müller-marienburgA. ReicheltM. Kohlhardt

subject

Pharmacologymedicine.medical_specialtyChemistryAdrenal cortexCell BiologyAngiotensin IICellular and Molecular Neurosciencemedicine.anatomical_structureEndocrinologyAnterior pituitaryInternal medicinemedicineMolecular MedicineMolecular BiologyDexamethasonemedicine.drug

description

The inhibition of 11-β-hydroxylase in the adrenal cortex with SU 4885 (metopiron) increases the ACTH-secretion. Val5-angiotensin II blocks the reaction of the anterior pituitary gland similarly as does dexamethasone. Mode and intensity of this action of angiotensin II, and the influence on rats treated as described, are studied.

https://doi.org/10.1007/bf02152145