6533b7d9fe1ef96bd126b8d8
RESEARCH PRODUCT
Corneal thickness differences between sexes after oxybuprocaine eye drops.
Alejandro CerviñoCésar Albarrán-diegoSantiago García-lázaroPablo Fernandez-garciaLaura Quiles-guiñauJuan A. Sanchis-gimenosubject
AdultMalemedicine.medical_specialtyAdolescentSalt lakeCorneaYoung AdultSex FactorsOphthalmologymedicineHumansProspective StudiesOxybuprocaineAnesthetics LocalBaseline valuesmedicine.diagnostic_testbusiness.industryCorneal TopographyOrgan SizeCorneal topographyOphthalmologyAnestheticFemaleOphthalmic SolutionsbusinessProcaineOptometrymedicine.drugdescription
PURPOSE We aimed to analyze the corneal thickness (CT) values of female and male subjects before and after instillation of oxybuprocaine 0.4% anesthetic eye drops. METHODS The CT of 30 female subjects and 28 male subjects was measured using scanning-slit corneal topography (Orbscan Topography System II, Orbscan, Inc, Salt Lake City, UT). Measurements were carried out before and 3 minutes after the instillation of oxybuprocaine 0.4% eye drops. RESULTS The difference between the baseline values and those obtained after anesthesia ranged as follows: male subjects: central, -26 to +24 μm; superior, -24 to +23 μm; inferior, -19 to +20 μm; nasal, -25 to +30 μm; and temporal, -21 to +20 μm; female subjects: central, -16 to +24 μm; superior, -19 to +32 μm; inferior, -14 to +34 μm; nasal, -19 to +33 μm; and temporal, -36 to +16 μm. No significant differences were found in any corneal location in male subjects. The differences were significant at inferior (p = 0.001) and nasal (p = 0.011) corneal sites in female subjects. CONCLUSIONS Oxybuprocaine anesthetic eye drops induce significant CT increases in female subjects but not in male subjects.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-11-01 | Optometry and vision science : official publication of the American Academy of Optometry |