6533b7d9fe1ef96bd126c4aa

RESEARCH PRODUCT

Implication of Normal Liver Enzymes in Liver Disease

Vincenza CalvarusoAntonio Craxì

subject

medicine.medical_specialtyPopulationChronic liver diseaseaminotransferases chronic hepatitis liver fibrosisGastroenterologySensitivity and SpecificityLiver diseaseVirologyInternal medicineNonalcoholic fatty liver diseasemedicineHumanseducationeducation.field_of_studyHepatologymedicine.diagnostic_testbusiness.industryLiver DiseasesFatty liverAlanine TransaminaseHepatitis Cmedicine.diseaseInfectious DiseasesLiverHepatic fibrosisLiver function testsbusiness

description

Summary.  Chronic liver disease is usually asymptomatic until its late stages and also significant hepatic necroinflammation and fibrosis may be present in persistently normal ALT levels HBV, HCV carriers or similarly, in patients with nonalcoholic fatty liver disease. Given the large number of persons in the general population which may harbor a clinically significant liver disease behind the screen of normal alanine aminotransferase, more attention should be devoted to future research for alternative noninvasive markers of liver damage.

http://hdl.handle.net/10447/44677