6533b7dbfe1ef96bd1270206

RESEARCH PRODUCT

Neoclerodane Diterpenoids from Teucrium maghrebinum

Franco PiozziMalik R. Y. Al-hilloMaria Luisa BondìSergio RosselliKaddour LamaraSegni LadjelMaurizio Bruno

subject

Pharmacologychemistry.chemical_classificationFolk medicineLamiaceaeMagnetic Resonance SpectroscopyMolecular StructurebiologyStereochemistryOrganic ChemistryPharmaceutical SciencePharmacognosybiology.organism_classificationMass SpectrometryTerpenoidAnalytical ChemistryTeucriumchemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoveryMolecular MedicineEpimerDiterpenesDiterpeneLactone

description

Eight neoclerodane diterpenoids were identified in the extract of the aerial parts of Teucrium maghrebinum. Three of these, 12-epi-teucjaponin A (1), 12-epi-montanin D (2), and 12-epi-montanin B (3), are new natural products, whereas five, teucjaponin A, montanin D, 19-deacetylteuscorodol, teusalvin C (4), and montanin B, are already known. These eight compounds form four pairs of epimers at carbon C-12.

https://doi.org/10.1021/np990510a