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6533b81ffe1ef96bd1277ad2

RESEARCH PRODUCT

Daratumumab for the Treatment of Multiple Myeloma

Jakub KrejcikTorben Plesner

subject

Cytotoxicity Immunologic0301 basic medicineOncologylcsh:Immunologic diseases. Allergymedicine.medical_specialtyAdenosineTreatment outcomeImmunologyDrug Evaluation PreclinicalComplementAntineoplastic AgentsMyelomaimmunomodulationImmunomodulation03 medical and health sciences0302 clinical medicineAntibodies monoclonalimmune system diseasesInternal medicineDaratumumabhemic and lymphatic diseasesAntineoplastic Combined Chemotherapy ProtocolsmedicineAnimalsHumansImmunology and AllergycomplementMultiple myelomaNeonatal Fc-receptorsClinical Trials as Topicbusiness.industryAntibody-Dependent Cell CytotoxicityAntibodies MonoclonalDaratumumabmedicine.diseasedaratumumabTrogocytosis3. Good healthTreatment Outcome030104 developmental biologymyelomaadenosine030220 oncology & carcinogenesisAntibody-dependent cell cytotoxicityMultiple Myelomabusinesslcsh:RC581-607CD38

description

This mini-review will summarize the present state of development of the CD38 antibody daratumumab for the treatment of multiple myeloma.

yearjournalcountryeditionlanguage
2018-06-04Frontiers in Immunology
10.3389/fimmu.2018.01228https://www.frontiersin.org/article/10.3389/fimmu.2018.01228/full
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