Attitude towards adherence in patients with schizophrenia at discharge

6533b820fe1ef96bd1279a20

RESEARCH PRODUCT

Attitude towards adherence in patients with schizophrenia at discharge

Wolfgang Gaebel Hans-jürgen Möller Lutz G. Schmidt Dieter Naber Joachim Klosterkötter Michael Obermeier Florian Seemüller Eckart Rüther Gerd Laux Michael Riedel Stefan Klingberg Markus Jäger Matthias R. Lemke Wolfgang Maier Thomas Messer Herbert Pfeiffer Isabella Heuser R. Schennach-wolff Markus Gastpar

subject

Adult Male medicine.medical_specialty Psychosis Time Factors medicine.drug_class medicine.medical_treatment Atypical antipsychotic Logistic regression Statistics Nonparametric Medication Adherence 03 medical and health sciences 0302 clinical medicine Rating scale Surveys and Questionnaires Multicenter trial medicine Psychoeducation Humans Psychiatry Biological Psychiatry Retrospective Studies Psychiatric Status Rating Scales Middle Aged medicine.disease Patient Discharge 3. Good health 030227 psychiatry Psychiatry and Mental health Schizophrenia Schizophrenia Female Schizophrenic Psychology Psychology Attitude to Health 030217 neurology & neurosurgery Follow-Up Studies Clinical psychology Psychopathology

description

Abstract Background Purpose of the present study was to assess the attitude towards adherence at discharge and to verify its predictability using anamnestic and sociodemographic variables, factors influencing clinical treatment as well as the medical treatment applied. Methods Attitude towards adherence was evaluated in 369 inpatients with schizophrenic spectrum disorders within a naturalistic multicenter trial using the Compliance Rating Scale (CRS) by Kemp. Biweekly ratings of the PANSS, UKU and the Subjective Well-being under Neuroleptic Treatment Scale (SWN-K) were applied. Logistic regression and CART analyses were used to determine significant predictor variables for the attitude towards adherence at discharge. Results Sixty-seven percent of the patients were rated to have an attitude of active participation and moderate participation (=positive attitude towards adherence) and 33% of the patients to have an attitude of passive acceptance, occasional or permanent reluctance towards treatment as well as refusing treatment (=negative attitude towards adherence). A significant correlation was found between patients with a positive attitude towards adherence and course of all PANSS subscales. Statistical analyses revealed a reduction in PANSS general psychopathology subscore, employment status, greater illness insight and treatment with atypical antipsychotics to be significantly predictive for a positive attitude towards adherence at discharge. Conclusions The importance of an adequate antipsychotic treatment as a precondition for a favourable adherence attitude and the need to incorporate adherence-focused psychotherapy and psychoeducation into daily clinical practice are highlighted.

year	journal	country	edition	language
2009-02-02	Journal of Psychiatric Research

https://doi.org/10.1016/j.jpsychires.2009.05.003