6533b821fe1ef96bd127c0ca
RESEARCH PRODUCT
Studies on metal-drug complexes. Crystal structure and characterization of μ-sulfato bromazepam copper(II) complex
José Antonio RealA. MossetM.c. MuñozJoaquín BorrásJean Galysubject
chemistry.chemical_classificationBromazepamChemistryStereochemistrychemistry.chemical_elementBridging ligandCrystal structureBiochemistryCopperInorganic ChemistryMetalCrystallographyOctahedronvisual_artmedicinevisual_art.visual_art_mediumMoleculeInorganic compoundmedicine.drugdescription
Abstract The compound Cu(Bromazepam) SO 4 having been synthesized, its crystal structure shows distorted octahedral environment for the Copper(II) ion. Because of the long Cu-O(4) length (2.90 A), we can consider that there is a semicoordinative interaction with the sulfate group acting as tridentate bridging ligand. The structure is a polymeric chain where dimeric units are linked by the oxygen (C-O(5)) atom of the Bromazepam carbonyl group. The drug consequently acts as a tridentate ligand in this compound. The magnetic results show a very weak antiferromagnetic interaction.
year | journal | country | edition | language |
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1987-11-01 | Journal of Inorganic Biochemistry |