6533b824fe1ef96bd12801a3

RESEARCH PRODUCT

Aflatoxins in organs and biological samples from children affected by kwashiorkor, marasmus and marasmic-kwashiorkor: A scoping review

Juan F. Merino-torresJosé Miguel SorianoDolores SilvestreMaría Morales-suárez-varelaAna Rubini

subject

MaleOchratoxin AAflatoxinLow proteinPhysiologyBiologyToxicologyFumonisinsProtein-Energy Malnutritionchemistry.chemical_compoundAflatoxinsmedicineHumansWeaningChildMycotoxinFumonisin B1KwashiorkorInfantfood and beveragesMycotoxinsmedicine.diseaseOchratoxinschemistryChild PreschoolKwashiorkorMarasmusFemale

description

Originally, the kwashiorkor is a pathology justified by the low consumption of proteins and high carbohydrates in weaned children. However, today, it can appear due to multifactorial causes, one of the hypotheses being the presence of aflatoxins in foods consumed by the child population and detected in biological fluids. The objective of this work is to scoping review the presence of aflatoxins in kwashiorkor, marasmus and marasmic-kwashiorkor from organs and biological samples in children. Results reflected that the presence of aflatoxins in kwashiorkor is greater compared to marasmic-kwashiorkor and marasmus in the organs and biological samples analyzed. The relationship of this mycotoxin with the pathology shows that it can affect both genders, even up to 12 years, in addition they are detected in eight biological samples and organs, except in the spleen, and in ten African countries and in the Philippines. The appearance of this pathology has been associated in children when after weaning they consume foods with low protein content and rich in carbohydrates, but coincidentally coincides with foods where the growth of aflatoxigenic fungi is more prevalent, and even the presence of other fungi that can generate other mycotoxins, such as ochratoxin A and fumonisin B1.

yearjournalcountryeditionlanguage
2020-10-01Toxicon
https://doi.org/10.1016/j.toxicon.2020.07.010