6533b824fe1ef96bd1280c4f
RESEARCH PRODUCT
Management of chemotherapy extravasation: ESMO–EONS Clinical Practice Guidelines
J.a. Perez FidalgoA. MarguliesL. García FabregatC. VidallAndrés CervantesF. Roilasubject
Drugmedicine.medical_specialtymedicine.medical_treatmentmedia_common.quotation_subjectAntidotesMEDLINECancer therapyAntineoplastic AgentsDiagnosis DifferentialRisk FactorsNeoplasmsHumansMedicineIntensive care medicinemedia_commonChemotherapyOncology (nursing)business.industryGeneral MedicineHematologymedicine.diseaseChemotherapy regimenExtravasationSurgeryClinical PracticeOncologybusinessInfiltration (medical)Extravasation of Diagnostic and Therapeutic Materialsdescription
Extravasation is the process by which any liquid (fluid or drug) accidentally leaks into the surrounding tissue. In terms of cancer therapy, extravasation refers to the inadvertent infiltration of chemotherapy into the subcutaneous or subdermal tissues surrounding the intravenous or intra-arterial administration site. Extravasated drugs are classified according to their potential for causing damage as ‘vesicant’, ‘irritant’ and ‘nonvesicant’ (Table 1). Some vesicant drugs are further classified into two groups: DNA binding and non-DNA binding. Allwood et al. (2002) divided the drugs into vesicants, exfoliants, irritants, inflammitants and neutrals.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-01-01 | Annals of Oncology |