6533b824fe1ef96bd1280cb2

RESEARCH PRODUCT

Intraoperative measurement of parathyroid hormone: A Copernican revolution in the surgical treatment of hyperparathyroidism

Carolina MaioneGiuseppe BuscemiSalvatore BuscemiRoberta AltomareGiuseppe DamianoMaria Concetta GiovialeAttilio Ignazio Lo Monte

subject

ParathyroidectomyReoperationmedicine.medical_specialtyHyperparathyroidism; Intraoperative PTH assay; Parathyroid hormone; Humans; Hyperparathyroidism; Parathyroid Hormone; Reoperation; Reproducibility of Results; Monitoring Intraoperative; Parathyroidectomy; Surgerymedicine.medical_treatmentParathyroid hormoneReproducibility of Result030209 endocrinology & metabolism03 medical and health sciences0302 clinical medicineMonitoring IntraoperativemedicineHumansSurgical treatmentParathyroidectomyHyperparathyroidismbusiness.industryHyperparathyroidismReproducibility of ResultsGeneral Medicinemedicine.diseaseIntraoperative PTH assaySurgeryParathyroid Hormone030220 oncology & carcinogenesisSurgeryParathyroid surgerybusinesshormones hormone substitutes and hormone antagonistsHuman

description

Intraoperative parathyroid hormone (PTH) monitoring in the setting of the operating room represents a valuable example of the rationale use of the laboratory diagnostic in a patient-oriented approach. Rapid intraoperative PTH (ioPTH) assay is a valid tool for an accurate evaluation of the success of parathyroid surgery. The reliability of the user-friendly portable systems as well as the collaboration between operators and surgical staff allow the one-site monitoring of the ioPTH decrements on the course of the surgical management of hyperparathyroidism. The rapid answer provided by an effective decrement of PTH during parathyroidectomy contributes dramatically to the efficacy of parathyroid surgery and the reduction of the number of re-operations. Therefore the dose of ioPTH is a valid and reliable support for the success of the intervention of parathyroidectomy at controlled costs.

10.1016/j.ijsu.2015.12.056http://hdl.handle.net/10447/245262