6533b825fe1ef96bd1281ee7

RESEARCH PRODUCT

The Utility of BDNF Detection in Assessing Severity of Huntington's Disease.

Klaudia PlintaMagdalena Doręgowska-stacheraMarcin RudzińskiMonika Rudzińska-barAndrzej PlewkaAgnieszka Krzak-kubicaKrzysztof PawlickiMagdalena Wójcik-pędziwiatrNikola Zmarzły

subject

Oncologymedicine.medical_specialtymedicine.diagnostic_testbusiness.industryNeurogenesisRNeurological examinationGeneral MedicineDiseasemedicine.diseaseMotor symptomsArticleBDNFHuntington's diseasenervous systemNeurotrophic factorsInternal medicineHealthy volunteersmedicineMedicinedisease severitybusinessCognitive impairmentHuntington’s disease

description

Brain-derived neurotrophic factor (BDNF) is involved in the survival and maturation of neurons, and also promotes and controls neurogenesis. Its levels are lowered in many neurodegenerative diseases, including Huntington’s disease (HD). Clinical pictures of HD can be very diverse, which makes it difficult to assess its severity

10.3390/jcm10215181https://pubmed.ncbi.nlm.nih.gov/34768699