6533b825fe1ef96bd1282853

RESEARCH PRODUCT

Sweet (hetero)aromatics: glycosylated templates for the construction of saccharide mimetics

Claudine SchlemmerClaudine SchlemmerTill OpatzStefan WeckStefan WeckChristine WiebeChristine Wiebe

subject

GlycosylationChemistryMetals and AlloysOligosaccharidesmacromolecular substancesGeneral ChemistryHydrocarbons AromaticCombinatorial chemistryCatalysisCycloadditionSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsTemplateCyclizationMaterials ChemistryCeramics and CompositesOrganic chemistrylipids (amino acids peptides and proteins)

description

Mono- and diglycosylated aromatics and heteroaromatics may serve as building blocks for the construction of metabolically stable mimetics of oligosaccharides. Methods for their preparation from monosaccharidic precursors by direct C-glycosylation, dipolar cycloaddition or Larock cyclization are described.

https://doi.org/10.1039/c1cc13078a