Low Dietary Magnesium and Overweight/Obesity in a Mediterranean Population: A Detrimental Synergy for the Development of Hypertension. The SUN Project

6533b828fe1ef96bd1287977

RESEARCH PRODUCT

Low Dietary Magnesium and Overweight/Obesity in a Mediterranean Population: A Detrimental Synergy for the Development of Hypertension. The SUN Project

Ligia J. Dominguez Alfredo Gea Carmen Sayón-orea Carmen Sayón-orea Mario Barbagallo Miguel Ruiz-canela Miguel Ruiz-canela Ujué Fresán Miguel A. Martínez‐gonzález Miguel ÁNgel Martínez-gonzález Miguel ÁNgel Martínez-gonzález Liz Ruiz-estigarribia Liz Ruiz-estigarribia

subject

0301 basic medicine Male obesity Settore MED/09 - Medicina Interna Mediterranean diet 030204 cardiovascular system & hematology Overweight magnesium Diet Mediterranean 0302 clinical medicine cohort studies Risk Factors Magnesium Longitudinal Studies Prospective Studies Uncategorized education.field_of_study Nutrition and Dietetics Incidence Middle Aged Cohort Hypertension Cohort studies Female medicine.symptom lcsh:Nutrition. Foods and food supply Cohort study Adult hypertension Population lcsh:TX341-641 Diet Surveys Article 03 medical and health sciences Young Adult Environmental health medicine Humans overweight Obesity Risk factor education 030109 nutrition & dietetics business.industry Feeding Behavior Overweight medicine.disease Obesity Diet Spain Self Report business diet Body mass index Food Science Follow-Up Studies

description

Hypertension is the strongest independent modifiable risk factor for cardiovascular disease. We aimed to investigate the association of magnesium intake with incident hypertension in a Mediterranean population, and the potential modification of this association by body mass index BMI. We assessed 14,057 participants of the SUN (Seguimiento Universidad de Navarra) prospective cohort (67.0% women) initially free of hypertension. At baseline, a validated 136-item food frequency questionnaire was administered. We used Cox models adjusted for multiple socio-demographic, anthropometric, and lifestyle factors, and prevalent conditions present at baseline. Among a mean 9.6 years of follow-up we observed 1406 incident cases of medically diagnosed hypertension. An inverse association in multivariable-adjusted models was observed for progressively higher magnesium intake up to 500 mg/d vs. intake &lt

year	journal	country	edition	language
2020-12-31	Nutrients

10.3390/nu13010125 http://dx.doi.org/10.3390/nu13010125