0000000000135981

AUTHOR

Carmen Sayón-orea

showing 11 related works from this author

Increased Adiposity Appraised with CUN-BAE Is Highly Predictive of Incident Hypertension. The SUN Project

2021

Overweight and obesity are growing worldwide and strongly associated with hypertension. The Clínica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) index is proposed as an optimal indicator of body fatness. We aimed to investigate the association of body fat as captured by the CUN-BAE index with incident hypertension in a Mediterranean population. We assessed 15,950 participants of the SUN (Seguimiento Universidad de Navarra) prospective cohort (63.7% women) initially free of hypertension. Participants completed follow-up questionnaires biennially. A validated 136-item food-frequency questionnaire was administered at baseline. We used Cox models adjusted for multiple confounders. …

AdultMalemedicine.medical_specialtyobesitySettore MED/09 - Medicina InternahypertensionPopulationOverweightCUN-BAEArticleFollow-Up StudieDiet Hypertensioncohort studiesInterquartile rangeInternal medicineMedicineHumansoverweightTX341-641Prospective cohort studyeducationeducation.field_of_studyadiposityNutrition and DieteticsNutrition. Foods and food supplybusiness.industryIncidenceRepeated measures designblood pressureMiddle Agedmedicine.diseaseObesitybody fatBlood pressureMultivariate AnalysisFemalemedicine.symptombusinessdietCohort studieFood ScienceCohort studyFollow-Up StudiesNutrients
researchProduct

Metabolic Syndrome Features and Excess Weight Were Inversely Associated with Nut Consumption after 1-Year Follow-Up in the PREDIMED-Plus Study.

2020

PREDIMED-PLUS investigators: et al.

0301 basic medicineNutMale*overweightmedicine.medical_specialtyMediterranean dietMedicine (miscellaneous)030209 endocrinology & metabolism*nut consumptionOverweightCohort Studies03 medical and health sciences0302 clinical medicine*Mediterranean dietRisk FactorsInternal medicinemedicineHumansNuts*obesityAged*metabolic syndrome2. Zero hungerMetabolic Syndrome030109 nutrition & dieteticsNutrition and Dietetics9. Industry and infrastructurebusiness.industrydigestive oral and skin physiologyfood and beveragesMiddle AgedOverweightmedicine.diseaseObesity3. Good healthDietBlood pressureCohort*excess weight*lifestyle*PREDIMED-Plus study*features of metabolic syndromeFemaleMetabolic syndromemedicine.symptombusiness*older adultsCohort studyFollow-Up Studies
researchProduct

Adherence to the Mediterranean Lifestyle and Desired Body Weight Loss in a Mediterranean Adult Population with Overweight: A PREDIMED-Plus Study

2020

Background. Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. Objectives. The aim of this study was to assess the association between the adherence to the Mediterranean lifestyle (diet and exercise) and the desired body weight loss in an adult Mediterranean population with overweight. Methods. Cross-sectional analysis in 6355 participants (3268 men; 3087 women) with metabolic syndrome and BMI (Body mass index) between 27.0 and 40.0 kg/m2 (55–75 years old) from the PREDIMED-Plus trial. Desired weight loss was the percentage of weight that participants wished to lose. It was categorized into four cut-offs of this perce…

MaleMediterranean dietObesidadejercicio físicoBody Mass Index:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]0302 clinical medicineSurveys and QuestionnairesAntineoplastic Combined Chemotherapy ProtocolsMedicinemediana edadeducation.field_of_studyanciano:Health Care::Health Care Quality Access and Evaluation::Quality of Health Care::Epidemiologic Factors::Age Factors [Medical Subject Headings]dietaprotocolos de quimioterapia antineoplásica combinada3. Good healthOlder adultsmetotrexatoprogramas de reducción de pesoObesitatlcsh:Nutrition. Foods and food supplyPersonas mayores frágilesIdeal weightLifestyles:Check Tags::Male [Medical Subject Headings]lcsh:TX341-641ArticleEstilo de vida03 medical and health sciences:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight [Medical Subject Headings]:Anthropology Education Sociology and Social Phenomena::Human Activities::Exercise [Medical Subject Headings]ifosfamidaHumanscisplatinoIfosfamideeducationExerciseAgedconducta alimentaria:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Metabolic Syndrome X [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology Social::Life Style [Medical Subject Headings]PREDIMED-Plusmedicine.diseaseObesityMethotrexate:Check Tags::Female [Medical Subject Headings]Desired weight lossMetabolic syndromeCisplatinBody mass indexDemographyobesitycumplimiento del pacientehumanos:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]Ideal Body Weightdesired weight loss:Health Care::Health Care Facilities Manpower and Services::Health Promotion::Weight Reduction Programs [Medical Subject Headings]OverweightDiet MediterraneanMediterranean lifestyle:Health Care::Health Care Facilities Manpower and Services::Health Services::Preventive Health Services::Health Promotion::Healthy People Programs [Medical Subject Headings]Weight loss030212 general & internal medicine:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Health Behavior::Patient Compliance [Medical Subject Headings]Abdominal obesityolder adults:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]2. Zero hungerNutrition and Dieteticsmediterranean lifestylesobrepeso:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet Mediterranean [Medical Subject Headings]Age Factorsideal weightMiddle AgedPeso corporal ideal:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Ideal Body Weight [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]Weight Reduction ProgramsBody imageFemalemedicine.symptompeso corporal idealEstils de vidadoxorrubicinabody imagePopulationImagen corporal030209 endocrinology & metabolism:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Feeding Behavior [Medical Subject Headings]overweightHealthy LifestyleObesity:Geographical Locations::Geographic Locations::Europe::Spain [Medical Subject Headings]business.industryíndice de masa corporalFeeding BehaviorOverweightDieta mediterráneaDietDoxorubicinSobrepesoPatient Compliance:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Body Image [Medical Subject Headings]businessFood Science
researchProduct

Consumption of iogurt, low-fat milk, and other low-fat dairy products is associated with lower risk of metabolic syndrome incidence in an elderly med…

2015

Background: The association between consumption of dairy products and the risk of developing metabolic syndrome (MetS) is unclear. Objective: The purpose of this study was to evaluate the associations between consumption of dairy products (total and different subtypes) and incident MetS in a Mediterranean population at high cardiovascular disease risk. Methods: We prospectively analyzed 1868 men and women (55–80 y old) without MetS at baseline, recruited from different PREDIMED (Prevenci´ on con Dieta Mediterr´ anea) centers between October 2003 and June 2009 and followed up until December 2010. MetS was defined according to updated, harmonized criteria. At baseline and yearly thereafter, w…

Malefood.ingredientPopulationMedicine (miscellaneous)Diet High-FatLower riskCohort StudiesfoodCheeseRisk FactorsEnvironmental healthSkimmed milkPrevalenceAnimalsHumansMedicineLongitudinal StudiesFood scienceeducationDiet Fat-RestrictedAgedAged 80 and overMetabolic SyndromeConsumption (economics)education.field_of_studyNutrition and Dieteticsbusiness.industryIncidenceIncidence (epidemiology)Productes lactis -- Aspectes nutritiusFeeding BehaviorMiddle AgedAnthropometryYogurtmedicine.diseaseMilkSpainElder Nutritional Physiological PhenomenaPersones grans -- AlimentacióFemaleDairy ProductsMetabolic syndromebusinessCohort study
researchProduct

Glycemic Dysregulations Are Associated With Worsening Cognitive Function in Older Participants at High Risk of Cardiovascular Disease: Two-Year Follo…

2021

The authors wish to thank the PREDIMED-Plus participants and staff for their engagement, as well as to the primary care centers involved in the study. We also thank the Cerca Programme of the Generalitat de Catalunya, and the CIBEROBN, CIBERESP and CIBERDEM initiatives of Instituto de Salud Carlos III in Spain, and the collaborators in the PRIME consortium for helpful input. The first version of the present article has been published in the public repository Research Square as a preprint publication of our work (44). We particularly thank Stephanie Nishi for her assistance with manuscript language revision.

Malemedicine.medical_specialtyCognition disordersEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismGlycemic ControlprediabetesType 2 diabetesdiabetes durationTrastorns de la cognicióDiseases of the endocrine glands. Clinical endocrinology03 medical and health scienceschemistry.chemical_compoundCognitionEndocrinology0302 clinical medicineInsulin resistanceinsulin resistanceDiabetes mellitusInternal medicinemedicineHumansHypoglycemic AgentsCognitive DysfunctionProspective StudiesPrediabetesglycated (glycosylated) hemoglobinCognitive declinecognitive functionAgedGlucose Metabolism DisordersOriginal ResearchGlycemicDiabetisbusiness.industryMalalties cardiovascularsDiabetesMiddle AgedRC648-665medicine.disease3. Good healthCardiovascular diseaseschemistryFemaletype 2 diabetesGlycated hemoglobinMetabolic syndromebusiness030217 neurology & neurosurgery
researchProduct

Low Dietary Magnesium and Overweight/Obesity in a Mediterranean Population: A Detrimental Synergy for the Development of Hypertension. The SUN Project

2020

Hypertension is the strongest independent modifiable risk factor for cardiovascular disease. We aimed to investigate the association of magnesium intake with incident hypertension in a Mediterranean population, and the potential modification of this association by body mass index BMI. We assessed 14,057 participants of the SUN (Seguimiento Universidad de Navarra) prospective cohort (67.0% women) initially free of hypertension. At baseline, a validated 136-item food frequency questionnaire was administered. We used Cox models adjusted for multiple socio-demographic, anthropometric, and lifestyle factors, and prevalent conditions present at baseline. Among a mean 9.6 years of follow-up we obs…

0301 basic medicineMaleobesitySettore MED/09 - Medicina InternaMediterranean diet030204 cardiovascular system & hematologyOverweightmagnesiumDiet Mediterranean0302 clinical medicinecohort studiesRisk FactorsMagnesiumLongitudinal StudiesProspective StudiesUncategorizededucation.field_of_studyNutrition and DieteticsIncidenceMiddle AgedCohortHypertensionCohort studiesFemalemedicine.symptomlcsh:Nutrition. Foods and food supplyCohort studyAdulthypertensionPopulationlcsh:TX341-641Diet SurveysArticle03 medical and health sciencesYoung AdultEnvironmental healthmedicineHumansoverweightObesityRisk factoreducation030109 nutrition & dieteticsbusiness.industryFeeding BehaviorOverweightmedicine.diseaseObesityDietSpainSelf ReportbusinessdietBody mass indexFood ScienceFollow-Up StudiesNutrients
researchProduct

Body shape trajectories and risk of breast cancer: results from the SUN ('Seguimiento Universidad De Navarra') Project.

2021

AbstractObjective:The aim of this study was to assess body shape trajectories in childhood and midlife in relation to subsequent risk of breast cancer (BC) in a Mediterranean cohort.Design:The ‘Seguimiento Universidad de Navarra’ (SUN) Project is a dynamic prospective cohort study of university graduates initiated in 1999. With a group-based modelling approach, we assessed body shape trajectories from age 5 to 40 years. Multivariable Cox regression models were used to estimate the hazard ratio (HR) for BC after the age of 40 years according to the body shape trajectory.Setting:City of Pamplona, in the North of Spain.Participants:6498 women with a mean age of 40 years (sd9).Results:We identi…

AdultAdolescentMedicine (miscellaneous)Breast NeoplasmsTrajectories03 medical and health sciencesBMIYoung Adult0302 clinical medicineBreast cancerBreast cancerRisk FactorsmedicineHumansBreast carcinogenesis030212 general & internal medicineObesityProspective StudiesProspective cohort studyChildNutrition and DieteticsProportional hazards modelbusiness.industrySomatotypesHazard ratioPublic Health Environmental and Occupational HealthCohortmedicine.diseaseObesityBody shapeSpain030220 oncology & carcinogenesisChild PreschoolCohortFemalebusinessBody mass indexDemographyFollow-Up StudiesResearch PaperPublic health nutrition
researchProduct

Leisure-Time physical activity, sedentary behaviour and diet quality are associated with metabolic syndrome severity: the PREDIMED-Plus Study

2020

The authors especially thank the PREDIMED-Plus participants for their enthusiastic collaboration, the PREDIMED-Plus personnel for outstanding support, and the personnel of all associated primary care centres for their exceptional effort. CIBEROBN, CIBERESP and CIBERDEM are initiatives of Instituto de Salud Carlos III, Spain. We thank the PREDIMED-Plus Biobank Network, part of the National Biobank Platform of Instituto de Salud Carlos III for storing and managing biological samples.

MaleSíndrome metabòlicaMediterranean diethumanosejercicio físico030204 cardiovascular system & hematologyOverweightSeverity of Illness Indexlaw.inventionchemistry.chemical_compound0302 clinical medicineSedentarismeRandomized controlled triallaw030212 general & internal medicineDepression (differential diagnoses)mediana edad2. Zero hungerMetabolic SyndromeancianoNutrition and Dietetics4. EducationMiddle Aged16. Peace & justiceMetabolic syndrome3. Good healthFemalemedicine.symptomlcsh:Nutrition. Foods and food supplymedicine.medical_specialtylcsh:TX341-641Article03 medical and health sciencesFood PreferencesMediterranean cookingLeisure ActivitiesInternal medicineMediterranean dietCuina mediterràniamedicineingesta energéticaHumansíndice de gravedad de la enfermedadExerciseMetabolic syndrome severityAgedbusiness.industryCholesterolPhysical activityactividades de ocioSedentary behaviourAnthropometryPhysical fitnessmedicine.diseaseObesitypreferencias alimenticiasSedentary behaviorCross-Sectional StudieschemistryDepression riskMetabolic syndromeSedentary BehaviorbusinessEnergy IntakeFood Scienceestudios transversalesCondició física
researchProduct

Yogurt consumption and abdominal obesity reversion in the PREDIMED study.

2016

Yogurt consumption and abdominal obesity reversion in the PREDIMED study. BACKGROUND AND AIMS: Evidence on the association yogurt consumption and obesity is not conclusive. The aim of this study was to prospectively evaluate the association between yogurt consumption, reversion of abdominal obesity status and waist circumference change in elderly. METHODS AND RESULTS: 4545 individuals at high cardiovascular risk were prospectively followed. Total, whole-fat and low-fat yogurt consumption were assessed using food frequency questionnaires. Generalized estimating equations were used to analyze the association between yogurt consumption and waist circumference change (measured at baseline and y…

0301 basic medicineMaleTime FactorsEndocrinology Diabetes and MetabolismMedicine (miscellaneous)0939-4753Logistic regressionDiet MediterraneanDieta mediterràniaRisk FactorsOdds RatioFood scienceProspective StudiesGeneralized estimating equationAbdominal obesityAged 80 and overBioquímica y tecnologíaNutrition and DieteticsAge Factorsfood and beveragesMiddle AgedCircumferenceYogurtDiet RecordsBiochemistry and technologyTreatment OutcomeCardiovascular DiseasesObesity AbdominalOlder adultsObesitatFemalemedicine.symptomWaist CircumferenceCardiology and Cardiovascular Medicinemedicine.medical_specialtyWaistIogurtBioquímica i biotecnologiaabdominal obesity03 medical and health sciencesInternal medicineWeight LossmedicineHumansAgedConsumption (economics)030109 nutrition & dieteticsbusiness.industryPREDIMED studyOdds ratiomedicine.diseaseObesityDietary FatsLogistic ModelsSpainMultivariate AnalysisLinear Modelsbusiness
researchProduct

Dietary Quality Changes According to the Preceding Maximum Weight: A Longitudinal Analysis in the PREDIMED-Plus Randomized Trial

2020

One-year dietary quality change according to the preceding maximum weight in a lifestyle intervention program (PREDIMED-Plus trial, 55–75-year-old overweight or obese adults; n = 5695) was assessed. A validated food frequency questionnaire was used to assess dietary intake. A total of 3 groups were made according to the difference between baseline measured weight and lifetime maximum reported weight: (a) participants entering the study at their maximum weight, (b) moderate weight loss maintainers (WLM), and (c) large WLM. Data were analyzed by General Linear Model. All participants improved average lifestyle. Participants entering the study at their maximum weight were the most susceptible …

Malecumplimiento del pacienteMediterranean diethumanosOverweightDiet Mediterraneanlaw.inventionencuestas sobre dietasClinical trials0302 clinical medicineRandomized controlled trialBehavior TherapyWeight losslawestudios prospectivosWeight managementMedicineLongitudinal StudiesProspective Studies030212 general & internal medicineskin and connective tissue diseasesmediana edadancianoNutrition and Dieteticssobrepesodietaresultado del tratamientoMaximum weightmodelos linealesMiddle AgedWeight Reduction ProgramsTreatment OutcomeBody imageDiet qualityCardiovascular Diseasesestilo de vidaprogramas de reducción de pesoFemaleDietaterapia conductistadietary patternDiet Healthypérdida de pesomedicine.symptommaximum weightlcsh:Nutrition. Foods and food supplybody imageenfermedades cardiovascularesPes corporalDietary patternlcsh:TX341-641030209 endocrinology & metabolismDiet SurveysArticle03 medical and health sciencesMediterranean dietWeight LossHumansObesityLife StyleobesidadAgedGeneral linear modelbusiness.industryPREDIMED-PlusBody weightOverweightPredimedDietLinear ModelsPatient Complianceestudios longitudinalesBody-Weight Trajectorysense organsbusinessAssaigs clínicsFood ScienceDemography
researchProduct

Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

2019

[Background]: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII®) was developed to appraise the inflammatory potential of the diet. [Objective]: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts.

AdultMale0301 basic medicinemedicine.medical_specialtyMediterranean diet030209 endocrinology & metabolismContext (language use)Type 2 diabetesDiet MediterraneanCritical Care and Intensive Care MedicineDietary inflammatory indexBody Mass IndexYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineMediterranean dietHumansMedicineObesityProspective StudiesMortalityProspective cohort studyRandomized Controlled Trials as TopicInflammation030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industrySmokingHazard ratioMiddle Agedmedicine.diseaseObesityDietC-Reactive ProteinDiabetes Mellitus Type 2CohortPatient ComplianceCohort studiesFemalebusinessCRPCohort study
researchProduct