Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion

6533b828fe1ef96bd1287b13

RESEARCH PRODUCT

Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion

Marc Altorfer Colin J. Henderson Colin J. Henderson Magdalena Westphal Johanna Beil Ulrike Naumann Juliane Perner Michael Schwarz Michael Schwarz Valerie Dubost Antonio Vitobello Antonio Vitobello Laurent Morawiec Jiang Zhu Jonathan G. Moggs Jonathan G. Moggs C. Roland Wolf C. Roland Wolf Mark Borowsky Rémi Terranova Arne Mueller Karen Kapur Alberto Del Rio-espinola

subject

Male 0301 basic medicine 6 3 Health Toxicology and Mutagenesis Gene regulatory network Plant Science SMAD Biology Biochemistry Genetics and Molecular Biology (miscellaneous)Epigenesis Genetic Mice 03 medical and health sciences 0302 clinical medicine medicine Animals Humans Gene Regulatory Networks Epigenetics Wnt Signaling Pathway Transcription factor Research Articles Ecology Gene Expression Profiling Liver Neoplasms Wnt signaling pathway Computational Biology 11 Chromatin Assembly and Disassembly medicine.disease Chromatin 3. Good health Chromatin 030104 developmental biology Phenobarbital 030220 oncology & carcinogenesis Cancer research Tumor promotion Liver cancer Research Article

description

This work explores quantitative chromatin accessibility, transcriptional and cis-acting gene regulatory variations underlying mouse strain–specific differences in drug-induced liver tumor promotion sensitivity.

year	journal	country	edition	language
2019-10-01	Life Science Alliance

https://doi.org/10.26508/lsa.201900461

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