6533b828fe1ef96bd12883ed
RESEARCH PRODUCT
Survival in patients with primary liver cancer, gallbladder and extrahepatic biliary tract cancer and pancreatic cancer in Europe 1999- 2007: Results of EUROCARE-5
Côme LepageRiccardo CapocacciaMonika HacklValerie LemmensEsther MolinaDaniela PierannunzioMilena SantAnnalisa TramaJean FaivreM. HacklN. ZielonkeW. OberaignerE. Van EyckenK. HenauZ. ValerianovaN. DimitrovaM. SekerijaM. ZvolskýL. DušekH. StormG. EngholmM. MägiT. AareleidN. MalilaK. SeppäM. VeltenX. TroussardV. BouvierG. LaunoyA.v. GuizardJ. FaivreA.m. BouvierP. ArveuxM. MaynadiéA.s. WoronoffM. RobaszkiewiczI. BaldiA. MonnereauB. TretarreN. BossardA. BelotM. ColonnaF. MoliniéS. BaraC. SchvartzB. Lapôtre-ledouxP. GrosclaudeM. MeyerR. StabenowS. LuttmannA. EberleH. BrennerA. NenneckeJ. EngelG. Schubert-fritschleJ. KieschkeJ. HeidrichB. HolleczekA. KatalinicJ.g. JónassonL. TryggvadóttirH. ComberG. MazzoleniA. BulatkoC. BuzzoniA. GiacominA. Sutera SardoP. MancusoS. FerrettiE. CrocettiA. CaldarellaG. GattaM. SantH. AmashC. AmatiP. BailiF. BerrinoS. BonfarnuzzoL. BottaF. Di SalvoR. FoschiC. MarguttiE. MeneghiniP. MinicozziA. TramaD. SerrainoL. Dal MasoR. De AngelisM. CaldoraR. CapocacciaE. CarraniS. FrancisciS. MalloneD. PierannunzioP. RoazziS. RossiM. SantaquilaniA. TavillaF. PannozzoS. BuscoL. BonelliM. VercelliV. GennaroP. RicciM. AutelitanoG. RandiM. Ponz De LeonC. MarchesiC. CirilliM. FuscoM.f. VitaleM. UsalaA. TrainaR. StaitiF. VitaleB. RavazzoloM. MichiaraR. TuminoP. Giorgi RossiE. Di FeliceF. FalciniA. IannelliO. SechiR. CesaraccioS. PifferA. MadedduF. TisanoS. MasperoA.c. FanettiR. ZanettiS. RossoP. CandelaT. ScuderiF. StracciF. BianconiG. TagliabueP. ContieroA.p. Dei TosS. GuzzinatiS. PildavaG. SmailyteN. CallejaD. AgiusT.b. JohannesenJ. RachtanS. GózdzR. MezykJ. BlaszczykM. BebenekM. Bielska-lasotaG. Forjaz De LacerdaM.j. BentoC. CastroA. MirandaA. Mayer-da-silvaF. NiculaD. CozaC. Safaei DibaM. Primic-zakeljE. AlmarC. RamírezM. ErrezolaJ. BidaurrazagaA. Torrella-ramosJ.m. Díaz GarcíaR. Jimenez-chillaronR. Marcos-grageraA. Izquierdo FontM.j. SanchezD.y.l. ChangC. NavarroM.d. ChirlaqueC. Moreno-iribasE. ArdanazJ. GalceranM. CarullaM. LambeS. KhanM. MousaviC. BouchardyM. UselS.m. EssH. FrickM. LorezS.m. EssC. HerrmannA. BordoniA. SpitaleI. KonzelmannO. VisserL. Van Der GeestR. OtterM. ColemanC. AllemaniB. RachetJ. VerneN. EaseyG. LawrenceT. MoranJ. RashbassM. RocheJ. WilkinsonA. GavinC. DonnellyD.h. BrewsterD.w. HuwsC. Whitesubject
Cancer Researchmedicine.medical_specialtySurvivalBiliary tract cancer; Cancer registry; Europe; Pancreatic cancer; Primary liver cancer; Survival; Time trends in survival; Oncology; Cancer ResearchPopulationSocio-culturaleTime trends in survivalGastroenterologyInternal medicinePancreatic cancermedicineeducationSurvival analysiseducation.field_of_studyRelative survivalbusiness.industryGallbladderPrimary liver cancerCancerPancreatic cancerCancer registrymedicine.diseaseCancer registryEuropeBiliary tract cancer ; Cancer registry ; Europe ; Pancreatic cancer ; Primary liver cancer ; Survival ; Time trends in survivalmedicine.anatomical_structureOncologyBiliary tract cancerLiver cancerbusinessdescription
Abstract Background The EUROCARE study collects and analyses survival data from population-based cancer registries (CRs) in Europe in order to provide data on between-country differences in survival and time trends in survival. Methods This study analyses data on liver cancer, gallbladder and extrahepatic biliary tract cancers (“biliary tract cancers”), and pancreatic cancer diagnosed in 2000–2007 from 88 CRs in 29 countries. Relative survival (RS) was estimated overall, by region, sex, age and period of diagnosis using the complete approach. Time trends in 5-year RS over 1999–2007 were also analysed using the period approach. Results The prognosis of the studied cancers was poor. Age-standardised 5-year RS was 12% for liver cancer, 17% for biliary tract cancers and 7% for pancreatic cancer. There were some between-country differences in survival. In general, RS was low in Eastern Europe and high in Central and Southern Europe. For all sites, 5-year RS was similar in men and women and decreased with advancing age. No substantial changes in survival were reported for pancreatic cancer over the period 1999–2007. On average, there was a crude increase in 5-year RS of 3 percentage points between the periods 1999–2001 and 2005–2007 for liver cancer and biliary tract cancers. Conclusions The major changes in imaging techniques over the study period for the diagnosis of the three studied cancers did not result in an improvement in the prognosis of these cancers. In the near future, new innovative treatments might be the best way to improve the prognosis in these cancers.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-01-01 |