6533b828fe1ef96bd12885c2

RESEARCH PRODUCT

Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect

Zeev ZalevskyNisan OzanaArun AnandYevgeny BeidermanAmir ShemerJavier GarciaSagi PolaniBaharam JavidiAriel Schwarz

subject

Blood GlucoseOptics and PhotonicsMaterials scienceLightRotationBiomedical EngineeringSolenoid01 natural sciencesMagneto-optic effectlaw.invention010309 opticsBiomaterialssymbols.namesakeSpeckle patternOpticslaw0103 physical sciencesFaraday effectHumansElectromagnetbusiness.industryLasers010401 analytical chemistryLaserAtomic and Molecular Physics and Optics0104 chemical sciencesElectronic Optical and Magnetic MaterialsMagnetic fieldMagnetssymbolsAlternating currentbusinessBlood Chemical Analysis

description

We experimentally verify a speckle-based technique for noncontact measurement of glucose concentration in the bloodstream. The final device is intended to be a single wristwatch-style device containing a laser, a camera, and an alternating current (ac) electromagnet generated by a solenoid. The experiments presented are performed in vitro as proof of the concept. When a glucose substance is inserted into a solenoid generating an ac magnetic field, it exhibits Faraday rotation, which affects the temporal changes of the secondary speckle pattern distributions. The temporal frequency resulting from the ac magnetic field was found to have a lock-in amplification role, which increased the observability of the relatively small magneto-optic effect. Experimental results to support the proposed concept are presented.

https://doi.org/10.1117/1.jbo.21.6.065001