6533b829fe1ef96bd128ab26

RESEARCH PRODUCT

Über die mikrobiologische Umwandlung N-haltiger Substrate. 4. Mitt.: Über die mikrobiologische Umwandlung von 5-Hydroxyindol durch Claviceps purpurea, Cordyceps militaris und Aspergillus oryzae

H. RochelmeyerD. WölfflingE. Mutschler

subject

biologyAspergillus oryzaeStrain (chemistry)ChemistryDrug DiscoveryCordyceps militarisBotanyPharmaceutical Sciencebiology.organism_classificationClaviceps purpureaMicrobiology

description

Aus 5-Hydroxyindol wird durch den Claviceps purpurea-Stamm 47 A 5-Hydroxytryptophan und ω-N-Acetyl-5-hydroxy-tryptophan, durch Cordyceps militaris ω-N-Acetyl-5-hydroxytryptophan und ω-N-Acetyl-serotonin, durch Aspergillus oryzae nur ω-N-Acetyl-serotonin in der Schuttelkultur gebildet. 5-Hydroxyindole, added to submerged cultures, is converted into 5-hydroxytryptophan and ω-N-acetyl-5-hydroxytryptophan by Claviceps purpurea strain 47 A; into ω-N-acetyl-5-hydroxytryptophan and ω-N-acetyl-serotonin by Cordiceps militaris; and only into-ω-N-acetyl-serotonin by Aspergillus oryzae.

https://doi.org/10.1002/ardp.19683010409