6533b82afe1ef96bd128c364
RESEARCH PRODUCT
Self-Immolative Linkers as Caps for the Design of Gated Silica Mesoporous Supports
Cristina GiménezAndrea BernardosFélix SancenónMargarita ParraRamón Martínez-máñezPablo GaviñaL. Alberto JuárezAna M. CosteroElena Añónsubject
Inorganic chemistryNanoparticlemesoporous materials010402 general chemistry01 natural sciencesCatalysisDeprotonationmolecular devicesQUIMICA ORGANICAPolymer chemistryQUIMICA ANALITICAMoietyMolecule010405 organic chemistryChemistryOrganic ChemistryQUIMICA INORGANICApH-responsive systemsGeneral ChemistryControlled release0104 chemical sciencesMesoporous organosilicasilicadyes/pigmentsHybrid materialMesoporous materialdescription
A new hybrid material based on sulforhodamine-B dye-loaded silica mesoporous nanoparticles capped with a self-immolative gate has been synthesized and characterized. The gated material's controlled release behavior is monitored under different pH conditions. Under acidic and neutral conditions, a low level of dye release is detected. However, at slightly basic pH, significant dye release occurs owing to deprotonation of the phenol moiety in the capping molecule, which results in its disassembly.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-09-01 |