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RESEARCH PRODUCT
Utilidad de los marcadores biológicos en la detección precoz y prevención del síndrome de burnout [Usefulness of biological markers in early detection and prevention of burnout syndrome]
Joao Paulo PereiraBeatriz Gómez-alcainaMarcelo Marcos Piva DemarzoJesus Montero-marinJavier García-campayosubject
Oncologymedicine.medical_specialtybiologybusiness.industryInterleukinInflammationBurnoutFibrinogenSurgeryPsychiatry and Mental healthClinical PsychologyImmune systemBlood pressureInternal medicineHeart ratemedicinebiology.proteinmedicine.symptomAntibodybusinessmedicine.drugdescription
Usefulness of biological markers in early detection and prevention of burnout syndrome Abstract: Burnout is associated with a worse health self-perception and greater physical and psychiatric comorbidity. The objective of this review is to summarize in a systematic way the main biomarkers associated with the burnout syndrome: cardiovascular (blood pressure, heart rate and variability of heart rate); sleep-related (quality, fragmentation, and sleep latency); associated with the hypothalamic-pituitary-adrenal axis and the sympathetic-adrenal-medullary axis (cortisol, sa- livary IgA, lysozime, α-amylase and chromogranin-A); related to the immune system (natural killer cells and mononuclear antibodies CD57 and CD16), and related to inflammation (TNF-α, IL-4 interleukins, fibrinogen, reactive C protein). In the next years, some of these biomarkers, mainly those related to the immune system and inflammation could become useful keys for the early de- tection and monitorization of this disorder.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-08-12 | Revista de Psicopatología y Psicología Clínica |