6533b82afe1ef96bd128cb96

RESEARCH PRODUCT

Chemical constituents of the root wood of Erythrina sacleuxii and determination of the absolute configuration of suberectin

Anja SchüfflerIshmael B. MasesaneCarina WeberGomotsang BojaseStefan PuschRunner R. T. MajindaTill OpatzJapheth O. Ombito

subject

AntifungalPyriculariabiologymedicine.drug_classChemistryAbsolute configurationGeneral Chemistry010402 general chemistrybiology.organism_classification01 natural sciences0104 chemical sciencesPhytochemicalMic valuesChemical constituentsmedicineErythrina sacleuxiiErythrinaNuclear chemistry

description

Phytochemical investigation on the root wood of Erythrina sacleuxii (Leguminosae) led to the isolation of nine secondary metabolites (1-9). Compound 1 was isolated from the genus Erythrina for the first time. The pure compounds were identified on the basis of comprehensive spectroscopic and spectrometric analyses, while their absolute configurations were determined based on chiroptical measurements. Compounds 5 and 6 showed weak antifungal activity against Pyricularia oryzae with MIC values of 20 µg/mL.
  
 Bull. Chem. Soc. Ethiop. 2020, 34(1), 135-140.
 DOI: https://dx.doi.org/10.4314/bcse.v34i1.12

https://doi.org/10.4314/bcse.v34i1.12