6533b82bfe1ef96bd128df0e

RESEARCH PRODUCT

Diagnostik der primär sklerosierenden Cholangitis: prospektiver Vergleich von MR-Cholangiographie mit endoskopisch retrograder Cholangiographie

P. GrebeManfred ThelenPeter MildenbergerA. W. LohseKatja OberholzerM. BantelmannT. Schadeck

subject

medicine.medical_specialtyCommon bile ductmedicine.diagnostic_testbusiness.industryIntrahepatic bile ductsmedicine.diseasedigestive systemGastroenterologyPrimary sclerosing cholangitisEndoscopymedicine.anatomical_structureCholangiographyInternal medicinemedicineEndoscopic retrograde cholangiographyRadiology Nuclear Medicine and imagingMagnet resonance imagingIn patientNuclear medicinebusiness

description

PURPOSE To assess the accuracy of MR cholangiography (MRC) in the diagnosis of primary sclerosing cholangitis (PSC) in comparison to endoscopic retrograde cholangiography (ERC). METHOD 20 patients with PSC were examined by ERC and MRC (1.0 T, HASTE sequence). Visualization and pathologic changes of the extra- and intrahepatic bile ducts were evaluated with both methods. RESULTS Mural irregularities of the common bile duct were seen with MRC in 6/7 cases, stenoses and dilatation of the common bile duct were detected correctly in all patients. Diffuse, multifocal strictures of the intrahepatic bile ducts were the most common intrahepatic findings and correctly diagnosed in almost all patients. Mural irregularities of the intrahepatic ducts in early stages may be missed by MRC because of the limited spatial resolution. MRC is superior to ERC in visualization of nonopacified intrahepatic ducts. CONCLUSIONS MRC is a reliable, non-invasive method to detect typical diagnostic features of PSC. It should be considered as an adjunct to ERC in patients with suspected PSC for primary diagnosis and as an alternate method for follow-up studies.

yearjournalcountryeditionlanguage
1998-12-01RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
https://doi.org/10.1055/s-2007-1015352