6533b82cfe1ef96bd128eb50

RESEARCH PRODUCT

Acylated triterpene saponins from Silene jenisseensis

Hildebert WagnerZhi-cen LouBernard HanquetZhen-hua CuiMarie Aleth Lacaille-dubois

subject

Magnetic Resonance SpectroscopyStereochemistryAcylationMolecular Sequence DataSaponinCaryophyllaceaePlant ScienceHorticulturePlant RootsBiochemistrylaw.inventionTriterpenelawCarbohydrate ConformationHumansMoleculeMedicine Chinese TraditionalOleanolic AcidMolecular BiologyChemiluminescencechemistry.chemical_classificationPlants MedicinalbiologyChemistryGeneral MedicineNuclear magnetic resonance spectroscopySaponinsbiology.organism_classificationTriterpenesIn vitroCarbohydrate SequenceHeteronuclear moleculeLuminescent MeasurementsGranulocytes

description

Abstract From the roots of Silene jenisseensis a new trans-p-methoxycinnamoyl triterpene saponin has been isolated along with its cis-p-methoxycinnamoyl isomer as an inseparable mixture. Their structures were established by chemical means and spectroscopic methods including 1D- and 2D-homonuclear and heteronuclear correlation NMR spectroscopy as 3-O-[β- d -galactopyranosyl -(1 → 2)-β- d -glucuronopyranosyl ]-28-O-[β- d -glucopyranosyl -(1 → 2)-α- l - rhamnopyranosyl -(1 → 2)-β- d -4-O-trans-p- methoxycinnamoyl-fucopyranosyl ] quillaic acid and its cis-isomer, respectively. They did not show any activity in the in vitro chemoluminescence granulocytes assay, but exhibited only a weak inhibitory effect in the cyclooxygenase inhibition assay.

yearjournalcountryeditionlanguage
1995-09-01Phytochemistry
https://doi.org/10.1016/0031-9422(95)00222-s