6533b82cfe1ef96bd128ec58
RESEARCH PRODUCT
Prognosis and cure of long-term cancer survivors: A population-based estimation.
L. Dal MasoC. PanatoS. GuzzinatiD. SerrainoS. FrancisciL. BottaR. CapocacciaA. TavillaA. GigliE. CrocettiM. RuggeG. TagliabueR. A. FilibertiG. CarrozziM. MichiaraS. FerrettiR. CesaraccioR. TuminoF. FalciniF. StracciA. TorrisiG. MazzoleniM. FuscoS. RossoF. TisanoA. C. FanettiG. M. SiniC. BuzzoniR. De AngelisS. VirdoneG. GattaM. ZorziS. MalloneF. ToffoluttiA. G. RussoA. L. CaiazzoL. MangoneW. MazzuccoF. PannozzoP. RicciG. GolaG. CandelaA. Sutera Sardosubject
0301 basic medicineOncologyMaleCancer ResearchTime FactorsSettore MED/42 - Igiene Generale E Applicata0302 clinical medicineCancer SurvivorsProstateNeoplasmsThyroid cancerOriginal Researcheducation.field_of_studyRelative survivalMortality rateMiddle Agedlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensPrognosispopulation-based cancer registriemedicine.anatomical_structureOncologyItaly030220 oncology & carcinogenesiscancer cure Italy population-based cancer registries prevalence survivalFemaleCancer PreventionAdultmedicine.medical_specialtypopulation-based cancer registriesAdolescentPopulationprevalenceSocio-culturalelcsh:RC254-282survival03 medical and health sciencesYoung AdultLife ExpectancyInternal medicinemedicinepopulation‐based cancer registriesHumansRadiology Nuclear Medicine and imagingcancer cureeducationAgedEstimationbusiness.industryCancerModels Theoreticalmedicine.disease030104 developmental biologyLife expectancycancer cure; Italy; population-based cancer registries; prevalence; survivalbusinessdescription
Background: Increasing evidence of cure for some neoplasms has emerged in recent years. The study aimed to estimate population-based indicators of cancer cure. Methods: Information on more than half a million cancer patients aged 15-74 years collected by population-based Italian cancer registries and mixture cure models were used to estimate the life expectancy of fatal tumors (LEFT), proportions of patients with similar death rates of the general population (cure fraction), and time to reach 5-year conditional relative survival (CRS) >90% or 95% (time to cure). Results: Between 1990 and 2000, the median LEFT increased >1 year for breast (from 8.1 to 9.4 years) and prostate cancers (from 5.2 to 7.4 years). Median LEFT in 1990 was >5 years for testicular cancers (5.8) and Hodgkin lymphoma (6.3) below 45 years of age. In both sexes, it was 95% was 90% was reached in 15 years. Conclusions: The study findings confirmed that several cancer types are curable. The awareness of the possibility of cancer cure has relevant clinical and social impacts. KEYWORDS cancer cure, Italy, population-based cancer registries, prevalence, survival
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 | Cancer medicine |