6533b82cfe1ef96bd128f3b5
RESEARCH PRODUCT
Die Bildung höherer Alkohole bei Aminosäuremangelmutanten von Saccharomyces cerevisiae III. Höhere Alkohole als Nebenprodukte der Aminosäuresynthese
F. RadlerD. Vollbrechtsubject
EthanolbiologyIsobutanoleducationMutantSaccharomyces cerevisiaeGeneral Medicinebiology.organism_classificationchemistry.chemical_compoundBiochemistrychemistryValineLeucineThreonineIsoleucinedescription
Summary The formation of higher alcohols as byproducts of the synthesis of threonine, isoleucine and valine was investigated using isogenic haploid and diploid mutant strains of Saccharomyces cerevisiae . Genetic markers were ade 2, leu 1. The growth rate, the formation of ethanol, the amino acid metabolism and the formation of higher alcohols were determined during fermentations in a synthetic medium. n-Propanol-1, 2-methylbutanol-l and isobutanol were synthesized parallel to ethanol formation during exponential and stationary growth phase. However, the formation of 3-methylbutanol-l from leucine was restricted to the exponential phase. A comparison of haploid and diploid strains revealed, apart from ethanol formation, no significant differences in the formation of higher alcohols or in amino acid metabolism.
year | journal | country | edition | language |
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1975-01-01 | Zentralblatt für Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite Naturwissenschaftliche Abteilung: Allgemeine, Landwirtschaftliche und Technische Mikrobiologie |