6533b82dfe1ef96bd12908d0

RESEARCH PRODUCT

Evaluation of the analgesic and CNS actions of different fractions from the methanol extract ofTeucrium flavum L.

L. MorenoBelén BeltránEduardo Primo-yúferaJuan V. EspluguesR. BelloSara Calatayud

subject

PharmacologyTraditional medicinebusiness.industryCns depressantCentral nervous systemAnalgesicBiological activityPharmacognosyTeucrium flavumlaw.inventionchemistry.chemical_compoundmedicine.anatomical_structurechemistrylawmedicineMethanolPhytotherapybusiness

description

Different fractions (F.1, F-3, F-5, F-6, F-7, F-8) of the methanol extract from Teucrium flavum L. have been tested for their central nervous system and analgesic activities at a dose of 200 mg/kg. Fractions F-1, F-3 and F-7 showed CNS depressant activity, while fractions F-5, F-6 and F-8 had a slight CNS stimulant action. Fractions F-5, F-6, F-7 and F-8 were responsible for the analgesic activity of the extract.

https://doi.org/10.1002/(sici)1099-1573(19980201)12:1<65::aid-ptr187>3.0.co;2-n