6533b82efe1ef96bd12926ce
RESEARCH PRODUCT
Analysis of 29 Y-chromosome SNPs in a single multiplex useful to predict the geographic origin of male lineages
Kinga BaloghClaus BørstingAlejandro Blanco-vereaMaria BrionBeate Stradmann-bellinghausenMagdalena BogusC.r. ThackerDenise Syndercombe-courtAngel CarracedoPeter M. SchneiderJuan J. SanchezNiels Morlingsubject
Forensic identificationGeneticsMultiplexSingle-nucleotide polymorphismGeneral MedicineTypingBiologyY chromosomeSingle-base extensionHaplogroupSNP genotypingdescription
Abstract The European Consortium “High throughput analysis of single nucleotide polymorphisms for the forensic identification of persons—SNPforID” has performed a selection of candidate Y-chromosome SNPs (single nucleotide polymorphisms) for making inferences on the geographic origin of an unknown sample. A “Major Y chromosome haplogroup typing kit” has been developed, which allows the multiplex amplification of 29 SNPs in a single reaction followed by a single base extension (SBE) reaction (minisequencing) and separation of the resulting extension products by capillary electrophoresis.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-04-01 | International Congress Series |