Prostaglandin A2 (PGA2) increases the coronary vascular resistance in the guinea-pig isolated heart preparation.

6533b82ffe1ef96bd12947c4

RESEARCH PRODUCT

Prostaglandin A2 (PGA2) increases the coronary vascular resistance in the guinea-pig isolated heart preparation.

subject

Isolated Heart Preparation Male medicine.medical_specialty Guinea Pigs Prostaglandin Pharmacology Guinea pig Cellular and Molecular Neuroscience chemistry.chemical_compound Internal medicine medicine Animals Molecular Biology Pharmacology Prostaglandins A Dose-Response Relationship Drug business.industry Cell Biology Isolated heart Coronary Vessels Myocardial Contraction medicine.anatomical_structure chemistry Vascular resistance Cardiology Molecular Medicine Female Vascular Resistance business

description

Prostaglandin A2 (PGA2) in concentrations of 1.5·10−8 to 3·10−6 M was found to produce concentration-dependent increase in the coronary vascular resistance of the guinea-pig isolated heart without alterations in myocardial contractile force and oxygen consumption.

year	journal	country	edition	language
1977-03-15	Experientia

10.1007/bf02002821 https://pubmed.ncbi.nlm.nih.gov/858364

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