6533b830fe1ef96bd1296ee2
RESEARCH PRODUCT
A novel multielectrode for epicardial recording with temperature control based in Peltier cells
Maria S. GuillemIsabel TraperoXavier Ibañez-cataláAndreu M. ClimentFrancisco J. ChorroAntonio Guill IbáñezJ. MilletE RosesLuis Such-miquelFrancisca PelechanoÁLvaro Tormossubject
HyperthermiaMaterials scienceTemperature controlCardiac electrophysiologyIsolated heartHypothermiamedicine.diseaseElectrophysiologyThermoelectric effectVentricular fibrillationElectronic engineeringmedicinemedicine.symptomBiomedical engineeringdescription
Electrophysiological parameters of the myocardium are influenced by temperature. Working with experimental models of isolated heart, the analysis of modulating effect exerted by local changes of temperature can provide some information about the mechanisms of certain arrhythmias and their electrophysiological bases, such as ventricular fibrillation. Conventional multiple electrodes do not seem to be appropriate, being necessary the development of specific devices. The design and implementation of a device adapted to these requirements is presented in this paper. This is a multi-electrode able to reproduce located and controlled conditions of hypothermia and hyperthermia, in a determined area of the epicardium while the electrical activity of this area is simultaneously recorded with enough resolution to obtain activation maps.
year | journal | country | edition | language |
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2009-01-01 |