6533b831fe1ef96bd12990e9

RESEARCH PRODUCT

Bilateral Wallerian degeneration of the medial cerebellar peduncles after ponto-mesencephalic infarction

Sabine FitzekSabine FitzekClemens FitzekClemens FitzekPeter Stoeter

subject

MaleWallerian degenerationPathologymedicine.medical_specialtyRetrograde DegenerationBrain Stem InfarctionsInfarctionCentral nervous system diseasePonsmedicineHumansRadiology Nuclear Medicine and imagingAgedmedicine.diagnostic_testEcho-Planar Imagingbusiness.industryMagnetic resonance imagingGeneral MedicineMiddle Agedmedicine.diseaseHyperintensityDiffusion Magnetic Resonance Imagingnervous systemFemaleTomography X-Ray ComputedWallerian DegenerationbusinessEcho planarDiffusion MRI

description

Three patients with acute large paramedian ponto-mesencephalic infarctions developed a bilateral retrograde degeneration of the medial cerebellar peduncles within 4 months after the insult. In an initial magnetic resonance imaging (MRI) within the first 2 weeks, the medial cerebellar peduncles showed normal intensities, but a control MRI after 4 months showed bright hyperintensities in the T2-TSE weighted images, and moderately increased signal intensities in echo planar imaging-diffusion weighted imaging were seen, possibly representing bilateral Wallerian degeneration of the cerebellar-pontine fibers.

https://doi.org/10.1016/s0720-048x(03)00132-3