6533b832fe1ef96bd129a10c

RESEARCH PRODUCT

�ber die Wirkung von Strophanthidin-3-bromacetat am Papillarmuskel des Meerschweinchens

U. FrickeW. Klaus

subject

PharmacologyInotropemedicine.medical_specialtybiologyDigitoxinATPasePharmacology toxicologyGeneral MedicineGuinea pigchemistry.chemical_compoundEndocrinologychemistryInternal medicinebiology.proteinmedicineDerivative (chemistry)medicine.drug

description

In experiments on isolated, electrically stimulated papillary muscles or auricles of guinea pig hearts some characteristics of the inotropic action of strophanthidin-3-bromaocetate (SBA), a derivative of k-strophanthidin which is supposed to be an irreversible inhibitor of the (Na+-K+)-activated ATPase, were studied and compared with the behaviour of k-strophanthidin and digitoxin.

https://doi.org/10.1007/bf01020074