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RESEARCH PRODUCT

First coincidences in pre-clinical Compton camera prototype for medical imaging

D. BurdetteW.l. RogersL. ZhangW. DulinskiNeal H. ClinthorneCarlos LacastaP. WeilhammerS.-j. ParkGabriela LlosaVladimir CindroE. ChesiD. ŽOntarJeffrey D SteinbergH. KaganScott J. WildermanJuan FusterAna C. MarquesAndrej StudenDirk MeierM. MikužShaun RoeN. MalakhovLi Han

subject

PhysicsSingle photon emission computed tomography (SPECT)Nuclear and High Energy PhysicsPhotonbusiness.industryPhysics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaGamma rayCompton scatteringScintillatorCollimated lightFull width at half maximum87.58.Ce; 29.40.GxOpticsSilicon pad detectorsCoincidentTracking and position-sensitive detectorsMedical imaging[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]businessInstrumentationNoise (radio)Compton camera

description

Abstract Compton collimated imaging may improve the detection of gamma rays emitted by radioisotopes used in single photon emission computed tomography (SPECT). We present a crude prototype consisting of a single 500 μm thick, 256 pad silicon detector with pad size of 1.4×1.4 mm 2 , combined with a 15×15×1 cm 3 NaI scintillator crystal coupled to a set of 20 photo multipliers. Emphasis is placed on the performance of the silicon detector and the associated read-out electronics, which has so far proved to be the most challenging part of the set-up. Results were obtained using the VATAGP3, 128 channel low-noise self-triggering ASIC as the silicon detector's front-end. The noise distribution ( σ ) of the spectroscopic outputs gave an equivalent noise charge (ENC) with a mean value of 〈σ〉=137 e with a spread of 10 e , corresponding to an energy resolution of 1.15 keV FWHM for the scattered electron energy. Threshold settings above 8.2 keV were required for stable operation of the trigger. Coincident Compton scatter events in both modules were observed for photons emitted by 57 Co source with principal gamma ray energies of 122 and 136 keV .

10.1016/j.nima.2004.06.014http://hal.in2p3.fr/in2p3-00024476