6533b835fe1ef96bd129ea31

RESEARCH PRODUCT

Plasma corticosteroids, free fatty acids, insulin and glucose in maternal blood during delivery.

H. WombacherG. J. KremerE. NieschlagK. Martin

subject

Blood Glucosemedicine.medical_specialtyLabor ObstetricChemistryInsulinmedicine.medical_treatmentGeneral MedicineMaternal bloodFatty Acids NonesterifiedDelivery ObstetricEndocrinologyAdrenal Cortex HormonesPregnancyStress PhysiologicalInternal medicineEndocrine GlandsDrug DiscoverymedicineMolecular MedicineHumansInsulinFemaleGenetics (clinical)Nervous control

description

Plasma-corticosteroids (PCS), free fatty acids (FFA), insulin and glucose were determined continously in maternal blood during the entire course of delivery, from the first stage of labour until 6 hours after delivery. A steep increase in the PCS and FFA concentration could be noticed from the onset of labour (PCS: 37,8±11.2 µg/100 ml;\(s_{\bar x} \),p≦0.01; FFA: 556±106.6 µVal/l;\(s_{\bar x} \),p≦0.01) to the birth of the child (PCS: 96.8±19,5 µg/100 ml;\(s_{\bar x} \),p≦0.01; FFA: 1129±220 µVal/l;\(s_{\bar x} \),p≦0.01) and basal levels were already reached 6 hours later (PCS: 36.0±18.5 µg/100 ml;\(s_{\bar x} \),p≦0.01; FFA: 538±192.8 µVal/l;\(s_{\bar x} \),p≦0.01). The rise of insulin and glucose is statistically less significant (p≦0.05). The results are discussed under the aspect of known endocrine and central nervous control mechanisms of mmetabilosm. There appears to be a strong corrclation between the intensity of stress and the concentration of PCS and FFA.

10.1007/bf01497215https://pubmed.ncbi.nlm.nih.gov/5523463