6533b835fe1ef96bd129ecc7

RESEARCH PRODUCT

The origin of postembryonic neuroblasts in the ventral nerve cord of Drosophila melanogaster.

Andreas ProkopGerhard M. Technau

subject

Central Nervous Systemanimal structuresNeurogenesisClone (cell biology)BiologyNeuroblastNeuroblasts/dk/atira/pure/subjectarea/asjc/2700/2702AnimalsBrdUMolecular BiologyCell lineageNeuroblast proliferationStem CellsfungiEmbryogenesisCell BiologyAnatomyGastrulaEmbryonic stem cellCell biologyGastrulationDrosophila melanogasterBromodeoxyuridineVentral nerve cordDrosophilaAnatomy/dk/atira/pure/subjectarea/asjc/1300/1307Ganglion mother cellDevelopmental Biology

description

ABSTRACT Embryonic and postembryonic neuroblasts in the thoracic ventral nerve cord of Drosophila melanogaster have the same origin. We have traced the development of threefold-labelled single precursor cells from the early gastrula stage to late larval stages. The technique allows in the same individual monitoring of progeny cells at embryonic stages (in vivo) and differentially staining embryonic and postembryonic progeny within the resulting neural clone at late postembryonic stages. The analysis reveals that postembryonic cells always appear together with embryonic cells in one clone. Further-more, BrdU labelling suggests that the embryonic neuroblast itself rather than one of its progeny resumes proliferation as a postembryonic neuroblast. A second type of clone consists of embryonic progeny only.

yearjournalcountryeditionlanguage
1991-01-01Development (Cambridge, England)
10.1242/dev.111.1.79https://pubmed.ncbi.nlm.nih.gov/1901786