6533b836fe1ef96bd12a0a02

RESEARCH PRODUCT

A cross-sectional survey of urinary iodine status in Latvia

Marina MakreckaLolita NeimaneMaija DambrovaAivars LejnieksUgis GruntmanisParsla VevereValdis PīrāgsEdgars LiepinshIlze KonradeIeva Strele

subject

Malemedicine.medical_specialty:MEDICINE [Research Subject Categories]Cross-sectional studyThyrotropinchemistry.chemical_elementUrineDisease clusterIodineLodized saltIodine; Deficiency; Iodized salt; Thyroid stimulating hormoneEnvironmental healthThyroid stimulating hormonePrevalenceHumansMedicineSodium Chloride DietaryChildSocioeconomic statusMedicine(all)Gynecologylcsh:R5-920business.industryInfant Newbornmedicine.diseaseLatviaIodine deficiencyIodised saltCross-Sectional StudieschemistryCreatinineAutomotive EngineeringIodized saltDeficiencyFemaleSelf ReportLodineUrinary iodinebusinesslcsh:Medicine (General)Iodine

description

Background and objective: A nationwide survey of schoolchildren was conducted to detect regional differences in urinary iodine excretion in Latvia and to compare the results with data from the newborn thyroid-stimulating hormone (TSH) screening database as well with the results of a similar study performed in Latvia 10 years ago. Materials and methods: We conducted a cross-sectional school-based cluster survey of 915 children aged 9–12 years in 46 randomly selected schools in all regions of Latvia. Urine samples, questionnaires on the consumption of iodized salt and information on socioeconomic status were collected. TSH levels in newborns were also measured. Results: The median creatinine-standardized urinary iodine concentration (UIC) in our study was 107.3 mg/g Cr. UIC measurements indicative of mild iodine deficiency were present in 31.6%, moderate deficiency in 11.9% and severe deficiency in 2.8% of the participants. The prevalence of iodine deficiency was the highest in the southeastern region of Latgale and the northeastern region of Vidzeme. The prevalence of TSH values &gt

10.1016/j.medici.2014.06.003http://www.sciencedirect.com/science/article/pii/S1010660X14000202