6533b836fe1ef96bd12a1cb0

RESEARCH PRODUCT

Sleep Induction by Intranasal Application of Melatonin

P. SemmG. GammelL. Vollrath

subject

endocrine systemmedicine.medical_specialtySleep inductionbusiness.industrymedicine.medical_treatmentPharmacologyPlaceboSleep in non-human animalsMelatoninEndocrinologyNasal sprayInternal medicinemedicinePotencyNasal administrationbusinesshormones hormone substitutes and hormone antagonistsHormonemedicine.drug

description

The sleep inducing potency of melatonin was tested in a double-blind study against placebo. The application form was a nasal spray with a 0.85% solution of melatonin in ethanol. 70% of the subjects fell asleep after treatment with the hormone.

https://doi.org/10.1016/b978-0-08-026400-4.50043-8