6533b837fe1ef96bd12a1d96
RESEARCH PRODUCT
Suppression of extinction with TMS in humans: from healthy controls to patients.
Carlo CaltagironeMassimiliano Oliverisubject
Visual perceptionmedicine.medical_treatmentINHIBITIONPosterior parietal cortexNeurosciences. Biological psychiatry. NeuropsychiatrySensory systemStimulationTACTILE SPACEBrain damageFunctional LateralityExtinction PsychologicalPARIETAL CORTEXParietal LobemedicineHumansCUTANEOUS STIMULIMOTOR CORTEXTRANSCRANIAL MAGNETIC STIMULATION; CUTANEOUS STIMULI; PULSE STIMULATION; PARIETAL CORTEX; TACTILE SPACE; MOTOR CORTEX; HUMAN BRAIN; NEGLECT; INHIBITION; PERCEPTIONPERCEPTIONSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaParietal lobeExtinctionGeneral Medicinemedicine.diseaseHUMAN BRAINTranscranial Magnetic StimulationSensation Disorders; Extinction Psychological; Humans; Space Perception; Transcranial Magnetic Stimulation; Parietal Lobe; Visual Perception; Touch; Functional LateralityTranscranial magnetic stimulationNeuropsychology and Physiological PsychologyNeurologyNEGLECTTouchExtinction (neurology)Space PerceptionPULSE STIMULATIONSensation DisordersVisual PerceptionPsychologicalSettore MED/26 - NeurologiaNeurology (clinical)medicine.symptomPsychologyNeuroscienceRC321-571Research Articledescription
We review a series of studies exemplifying some applications of single-pulse and paired-transcranial magnetic stimulation (TMS) in the study of spatial attention and of its deficits. We will focus primarily on sensory extinction, the failure to consciously perceive a contralesional sensory stimulus only during bilateral stimulation of homologous surfaces. TMS studies in healthy controls show that it is possible either to interfere or modulate the excitability of the parietal cortex during sensory (i.e. tactile and visual) attentional tasks, thus reproducing a condition of virtual extinction. TMS studies in patients with unilateral (mainly right) brain damage show that the modulation of the unbalance in cortical excitability between the two cerebral hemispheres transiently improves contralesional sensory extinction. These studies show the possible application of TMS not only as a research method in healthy subjects, but also as a tool for inducing brain excitability changes in patients with sensory extinction, which could be useful for supporting the rehabilitation of this deficit.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-12-07 | Behavioural neurology |