6533b837fe1ef96bd12a294d
RESEARCH PRODUCT
A pilot study comparing different dose levels and administration schedules of interferon-α2b combined with epirubicin for prevention of recurrence in bladder cancer
Carlo PavoneM. Pavone-macalusoCorselli GSerrettasubject
OncologyCancer Researchmedicine.medical_specialtyAlpha interferonPilot ProjectsInterferon alpha-2Text miningRecurrenceInterferonInternal medicineAntineoplastic Combined Chemotherapy ProtocolsHumansMedicinePharmacology (medical)EpirubicinPharmacologyBladder cancerbusiness.industryInterferon-alphamedicine.diseaseRecombinant ProteinsAdministration IntravesicalUrinary Bladder NeoplasmsOncologybusinessmedicine.drugEpirubicindescription
A pilot study in 62 patients has been carried out to evaluate the combination of epirubicin and interferon (IFN)-alpha 2b using different doses and schedules of intravesical administration in the prevention of recurrence of bladder cancer. Preliminary results show greater prophylactic efficacy not only when higher doses of epirubicin and IFN-alpha 2b are used but also when a larger interval between instillation of the compounds was used.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1992-05-01 | Anti-Cancer Drugs |