6533b839fe1ef96bd12a5c3e

RESEARCH PRODUCT

High-frequency rTMS improves time perception in Parkinson disease.

Paolo StanzioneMassimiliano OliveriCarlo CaltagironeSara TorrieroLivia BrusaGiacomo Koch

subject

MaleTRANSCRANIAL MAGNETIC STIMULATIONCORTEXmedicine.medical_treatmentmedia_common.quotation_subjectFrontal Lobe; Magnetics; Parkinson Disease; Humans; Treatment Outcome; Aged; Time Perception; Middle Aged; Prefrontal Cortex; Perceptual Disorders; Male; FemalePrefrontal CortexDiseasebehavioral disciplines and activitiesNOCentral nervous system diseasePerceptual DisordersMagneticsDegenerative diseasePerceptionmental disordersBasal gangliamedicineHumansmedia_commonAgedSupplementary motor areaSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaParkinson DiseaseTime perceptionMiddle Agedmedicine.diseaseFrontal LobeTranscranial magnetic stimulationmedicine.anatomical_structureTreatment Outcomenervous systemTime PerceptionSettore MED/26 - NeurologiaFemaleNeurology (clinical)PsychologyNeurosciencepsychological phenomena and processes

description

Patients with Parkinson disease (PD) are impaired in time processing. The authors investigated the effects of high-frequency (5 Hz) repetitive transcranial magnetic stimulation (rTMS) in patients with PD performing a time reproduction task. The authors found significant improvement in time processing induced by rTMS when trains were applied over the right dorsolateral prefrontal cortex (DLPFC) but not over the supplementary motor area, suggesting that the circuit involving the basal ganglia and the DLPFC might constitute the neural network subserving time perception.

yearjournalcountryeditionlanguage
2004-12-28Neurology
10.1212/01.wnl.0000147336.19972.82https://pubmed.ncbi.nlm.nih.gov/15623713