6533b839fe1ef96bd12a6552
RESEARCH PRODUCT
Screening of ligands for the Ullmann synthesis of electron-rich diaryl ethers
Nicola OttoTill Opatzsubject
chemistry.chemical_classificationC–O bond formationDenticityBase (chemistry)catalysisArylOrganic Chemistrynucleophilic aromatic substitutiondiaryl ethersUllmann-type couplingCombinatorial chemistryFull Research PaperCatalysislcsh:QD241-441Chemistrychemistry.chemical_compoundchemistrylcsh:Organic chemistryNucleophilic aromatic substitutionPotassium phosphateOrganic chemistrylcsh:QAcetonitrilelcsh:ScienceCopper iodidedescription
In the search for new ligands for the Ullmann diaryl ether synthesis, permitting the coupling of electron-rich aryl bromides at relatively low temperatures, 56 structurally diverse multidentate ligands were screened in a model system that uses copper iodide in acetonitrile with potassium phosphate as the base. The ligands differed largely in their performance, but no privileged structural class could be identified.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-04-27 | Beilstein Journal of Organic Chemistry |