6533b83afe1ef96bd12a7af0

RESEARCH PRODUCT

Malignant fibrous histiocytoma of the renal capsule

Helmut E. GabbertR. WagnerE. Becht

subject

Cancer Researchmedicine.medical_specialtyPathologyHistogenesislaw.inventionDiagnosis DifferentialRenal capsulelawRenal cell carcinomaInternal medicinemedicineHumansHistiocyteAgedHematologyHistiocytoma Benign Fibrousbusiness.industryGeneral Medicinemedicine.diseaseKidney Neoplasmsmedicine.anatomical_structureOncologyGiant cellFemaleDifferential diagnosisElectron microscopebusiness

description

We report about an extremely rare case of malignant fibrous histiocytoma (MFH) of the renal capsule. The tumor is composed of fibroblast-like cells arranged in a storiform pattern and histiocyte-like cells with multinucleated giant cells, both showing no iron reaction. Characteristic of the histiocytic quality of the tumor are numerous PAS-positive intracytoplasmic droplets which can be identified as erythrophagosomes only under the electron microscope. Emphasis is put on the preoperative differential diagnosis of the tumor from renal cell carcinoma as well as on its histogenesis and prognosis.

https://doi.org/10.1007/bf00410689