6533b850fe1ef96bd12a8425
RESEARCH PRODUCT
Solitary polypoid laryngeal xanthoma.
Diego Collado-martínBeatriz Vera-sireraFrancisco Vera-semperesubject
Pathologymedicine.medical_specialtyCordmedicine.diagnostic_testbusiness.industryHepatitis C virusLaryngoscopyContext (language use)Case ReportGeneral MedicineXanthomamedicine.diseasemedicine.disease_causelcsh:Otorhinolaryngologylcsh:RF1-547PathogenesisDiabetes mellitusMedicinebusinessPathologicaldescription
We report the case of a 51-year-old male smoker with diabetes mellitus and hyperlipidaemia and a long history of human immunodeficiency virus (HIV)/hepatitis C virus (HCV) infection treated with various antiretroviral regimes, who was referred to the otolaryngology department with progressive dysphonia. Fibre-optic laryngoscopy showed a solitary, yellowish-white pedunculated polyp on the anterior third of the left cord, with no other abnormality. Pathological analysis revealed a polypoid laryngeal xanthoma that was immunoreactive against CD68, perilipin, and adipophilin. This unusual laryngeal lesion in the clinical context of our patient suggests a possible role of antiretroviral treatment in the pathogenesis of these xanthomas.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-03-31 | Case reports in otolaryngology |