6533b853fe1ef96bd12ac261

RESEARCH PRODUCT

The actual management of colorectal liver metastases

Susana Rosello KeranenLuis SabaterMarina Garcés-albirElena Muñoz-fornerMarisol Huerta AlvaroDimitri DorcarattoLeticia Pérez-santiago

subject

ReoperationSurgical resectionmedicine.medical_specialtyOrganoplatinum CompoundsColorectal cancerLeucovorinDisease030230 surgery03 medical and health sciencesHepatic Artery0302 clinical medicineAntineoplastic Combined Chemotherapy ProtocolsHepatectomyHumansInfusions Intra-ArterialMedicineMicrowavesRadiofrequency Ablationbusiness.industryGeneral surgeryLiver NeoplasmsMargins of ExcisionPrognosismedicine.diseaseLiver TransplantationElectroporation030220 oncology & carcinogenesisCamptothecinSurgeryFluorouracilColorectal Neoplasmsbusiness

description

Colorectal cancer is one of the most frequent cancers in the world and between 50% and 60% of patients will develop colorectal liver metastases (CRLM) during the disease. There have been great improvements in the management of CRLM during the last decades. The combination of modern chemotherapeutic and biological systemic treatments with aggressive surgical resection strategies is currently the base for the treatment of patients considered unresectable until few years ago. Furthermore, several new treatments for the local control of CRLM have been developed and are now part of the arsenal of multidisciplinary teams for the treatment of these complex patients. The aim of this review was to summarize and update the management of CRLM, its controversies and relevant evidence.

yearjournalcountryeditionlanguage
2020-11-01Minerva Chirurgica
https://doi.org/10.23736/s0026-4733.20.08436-9