6533b853fe1ef96bd12accd0
RESEARCH PRODUCT
Swim-up procedure selects spermatozoa with longer telomere length.
Rebeca SantisoMarcos MeseguerJaime GosálvezJosé Luis FernándezNicolás GarridoMaría Tamayosubject
Maleendocrine systemeducation.field_of_studyurogenital systemHealth Toxicology and MutagenesisPopulationDNA FragmentationBiologyTelomereSpermMolecular biologySpermatozoaChromatinTelomerechemistry.chemical_compoundReal-time polymerase chain reactionchemistryGeneticsSperm MotilityDNA fragmentationHumanseducationMolecular Biologyreproductive and urinary physiologyDNAdescription
Telomere length and sperm DNA fragmentation were determined in sperm samples from 27 patients, using a quantitative PCR (Q-PCR) assay and the Sperm Chromatin Dispersion (SCD) test, respectively. Comparisons of the samples before and after swim-up processing demonstrated that this procedure selects a sperm population with longer average telomere size and lower frequency of sperm cells with fragmented DNA.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-06-01 | Mutation research |