6533b853fe1ef96bd12ad349

RESEARCH PRODUCT

Die Haftung verschiedener Cardenolide am Papillarmuskel und einer mikrosomalen ATPase des Meerschweinchenherzens

W. KlausU. Fricke

subject

PharmacologyGuinea pigchemistry.chemical_compoundbiologyBiochemistryChemistryATPasePharmacology toxicologybiology.proteinCardenolideGeneral Medicine

description

In experiments on isolated electrically stimulated guinea pig papillary muscles and on isolated cardiac Na+-K+-activated ATPase preparations the action and the reversibility of action of 3 different cardenolides-digitoxin, k-strophanthidin and strophanthidin-3-bromoacetate (SBA) (supposed to be an irreversible inhibitor of the transport ATPase)-were studied.

https://doi.org/10.1007/bf01020075