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RESEARCH PRODUCT
Exploring the Physical Limits of Saturation Contrast in Magnetic Resonance Imaging
Yushen ZhangM. LapertSteffen J. GlaserMartin A. JanichDominique Sugnysubject
PhysicsMultidisciplinarymedicine.diagnostic_testModel systemMagnetic resonance imagingRangingOptimal control01 natural sciencesSEQUENCENMRSIGNAL3. Good health030218 nuclear medicine & medical imagingComputational physics03 medical and health sciences0302 clinical medicineDESIGN0103 physical sciencesEXCITATIONmedicine010306 general physicsSaturation (magnetic)Excitationdescription
International audience; Magnetic Resonance Imaging has become nowadays an indispensable tool with applications ranging from medicine to material science. However, so far the physical limits of the maximum achievable experimental contrast were unknown. We introduce an approach based on principles of optimal control theory to explore these physical limits, providing a benchmark for numerically optimized robust pulse sequences which can take into account experimental imperfections. This approach is demonstrated experimentally using a model system of two spatially separated liquids corresponding to blood in its oxygenated and deoxygenated forms.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-08-20 |